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Investigating the Role of T-bet(+) B Cells (ABCs/DN) in the Immunopathogenesis of Systemic Lupus Erythematosus

BACKGROUND: Age-associated B cells (ABCs) constitute a B cell subset, defined as CD19(+)CD21(−)CD11c(+), that expands continuously with age and accumulates strongly in individuals with autoimmune and/or infectious diseases. In humans, ABCs are principally IgD(−)CD27(−) double-negative (DN) B cells....

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Detalles Bibliográficos
Autores principales: Sachinidis, Athanasios, Trachana, Maria, Taparkou, Anna, Gavriilidis, George, Verginis, Panayotis, Psomopoulos, Fotis, Adamichou, Christina, Boumpas, Dimitrios, Garyfallos, Alexandros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Mediterranean Journal of Rheumatology (MJR) 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201091/
https://www.ncbi.nlm.nih.gov/pubmed/37223601
http://dx.doi.org/10.31138/mjr.34.1.117