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Combining histological grade, TILs, and the PD-1/PD-L1 pathway to identify immunogenic tumors and de-escalate radiotherapy in early breast cancer: a secondary analysis of a randomized clinical trial

BACKGROUND: The implementation of immunological biomarkers for radiotherapy (RT) individualization in breast cancer requires consideration of tumor-intrinsic factors. This study aimed to investigate whether the integration of histological grade, tumor-infiltrating lymphocytes (TILs), programmed cell...

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Detalles Bibliográficos
Autores principales: Stenmark Tullberg, Axel, Sjöström, Martin, Tran, Lena, Niméus, Emma, Killander, Fredrika, Kovács, Anikó, Lundstedt, Dan, Holmberg, Erik, Karlsson, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201214/
https://www.ncbi.nlm.nih.gov/pubmed/37208129
http://dx.doi.org/10.1136/jitc-2022-006618