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Combining histological grade, TILs, and the PD-1/PD-L1 pathway to identify immunogenic tumors and de-escalate radiotherapy in early breast cancer: a secondary analysis of a randomized clinical trial
BACKGROUND: The implementation of immunological biomarkers for radiotherapy (RT) individualization in breast cancer requires consideration of tumor-intrinsic factors. This study aimed to investigate whether the integration of histological grade, tumor-infiltrating lymphocytes (TILs), programmed cell...
Autores principales: | Stenmark Tullberg, Axel, Sjöström, Martin, Tran, Lena, Niméus, Emma, Killander, Fredrika, Kovács, Anikó, Lundstedt, Dan, Holmberg, Erik, Karlsson, Per |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201214/ https://www.ncbi.nlm.nih.gov/pubmed/37208129 http://dx.doi.org/10.1136/jitc-2022-006618 |
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