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New pro-inflammatory cytokine IL-40 is produced by activated neutrophils and plays a role in the early stages of seropositive rheumatoid arthritis

OBJECTIVE: Interleukin (IL)-40 is a new cytokine related to immune system function and malignancies. Recently, an association of IL-40 with rheumatoid arthritis (RA) and externalisation of neutrophil extracellular traps (NETosis) was found. As neutrophils are implicated in RA development, we investi...

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Detalles Bibliográficos
Autores principales: Navrátilová, Adéla, Bečvář, Viktor, Hulejová, Hana, Tomčík, Michal, Štolová, Lucie, Mann, Heřman, Růžičková, Olga, Šléglová, Olga, Závada, Jakub, Pavelka, Karel, Vencovský, Jiří, Šenolt, Ladislav, Andrés Cerezo, Lucie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201233/
https://www.ncbi.nlm.nih.gov/pubmed/37208028
http://dx.doi.org/10.1136/rmdopen-2022-002894