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3,5,3'-Triiodo-L-Thyronine Regulates Actin Cytoskeleton Dynamic in The Differentiated PC-12 Cells during Hypoxia through An αvβ3 Integrin

OBJECTIVE: Thyroid hormones are involved in the pathogenesis of various neurological disorders. Ischemia/hypoxia that induces rigidity of the actin filaments, which initiates neurodegeneration and reduces synaptic plasticity. We hypothesized that thyroid hormones via alpha-v-beta-3 (αvβ3) integrin c...

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Detalles Bibliográficos
Autores principales: Barbakadze, Tamar, Kvergelidze, Elisabed, Bátor, Judit, Szeberényi, József, Mikeladze, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201356/
https://www.ncbi.nlm.nih.gov/pubmed/37210645
http://dx.doi.org/10.22074/CELLJ.2022.557501.1059