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The ADAR1 editome reveals drivers of editing-specificity for ADAR1-isoforms

Adenosine deaminase acting on RNA ADAR1 promotes A-to-I conversion in double-stranded and structured RNAs. ADAR1 has two isoforms transcribed from different promoters: cytoplasmic ADAR1p150 is interferon-inducible while ADAR1p110 is constitutively expressed and primarily localized in the nucleus. Mu...

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Detalles Bibliográficos
Autores principales: Kleinova, Renata, Rajendra, Vinod, Leuchtenberger, Alina F, Lo Giudice, Claudio, Vesely, Cornelia, Kapoor, Utkarsh, Tanzer, Andrea, Derdak, Sophia, Picardi, Ernesto, Jantsch, Michael F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201426/
https://www.ncbi.nlm.nih.gov/pubmed/37026479
http://dx.doi.org/10.1093/nar/gkad265