A new method to synthesize multiple gRNA libraries and functional mapping of mammalian H3K4me3 regions

Genetic screening based on the clustered regularly interspaced palindromic repeat (CRISPR) system has been indicated to be a powerful tool for identifying regulatory genes or cis-elements. However, when applying CRISPR screens to pinpoint functional elements at particular loci, a large number of gui...

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Detalles Bibliográficos
Autores principales: Pan, Chen, Li, Ran, Shui, Liyan, Xiao, Zhengyun, Wang, Yali, Zhu, Jing, Wu, Chao, Zhang, Long, Jia, Junling, Zheng, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201432/
https://www.ncbi.nlm.nih.gov/pubmed/36938898
http://dx.doi.org/10.1093/nar/gkad198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201432/
https://www.ncbi.nlm.nih.gov/pubmed/36938898
http://dx.doi.org/10.1093/nar/gkad198

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