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RNA origami scaffolds facilitate cryo-EM characterization of a Broccoli–Pepper aptamer FRET pair

Cryogenic electron microscopy (cryo-EM) is a promising method for characterizing the structure of larger RNA structures and complexes. However, the structure of individual aptamers is difficult to solve by cryo-EM due to their low molecular weight and a high signal-to-noise ratio. By placing RNA apt...

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Detalles Bibliográficos
Autores principales: Sampedro Vallina, Néstor, McRae, Ewan K S, Hansen, Bente Kring, Boussebayle, Adrien, Andersen, Ebbe Sloth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201433/
https://www.ncbi.nlm.nih.gov/pubmed/36999628
http://dx.doi.org/10.1093/nar/gkad224