Oncogenic YAP mediates changes in chromatin accessibility and activity that drive cell cycle gene expression and cell migration

YAP, the key protein effector of the Hippo pathway, is a transcriptional co-activator that controls the expression of cell cycle genes, promotes cell growth and proliferation and regulates organ size. YAP modulates gene transcription by binding to distal enhancers, but the mechanisms of gene regulat...

Descripción completa

Detalles Bibliográficos
Autores principales: Fetiva, Maria Camila, Liss, Franziska, Gertzmann, Dörthe, Thomas, Julius, Gantert, Benedikt, Vogl, Magdalena, Sira, Nataliia, Weinstock, Grit, Kneitz, Susanne, Ade, Carsten P, Gaubatz, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201438/
https://www.ncbi.nlm.nih.gov/pubmed/36864753
http://dx.doi.org/10.1093/nar/gkad107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201438/
https://www.ncbi.nlm.nih.gov/pubmed/36864753
http://dx.doi.org/10.1093/nar/gkad107

Ejemplares similares