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Oncogenic YAP mediates changes in chromatin accessibility and activity that drive cell cycle gene expression and cell migration
YAP, the key protein effector of the Hippo pathway, is a transcriptional co-activator that controls the expression of cell cycle genes, promotes cell growth and proliferation and regulates organ size. YAP modulates gene transcription by binding to distal enhancers, but the mechanisms of gene regulat...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201438/ https://www.ncbi.nlm.nih.gov/pubmed/36864753 http://dx.doi.org/10.1093/nar/gkad107 |