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Requirements for mammalian promoters to decode transcription factor dynamics

In response to different stimuli many transcription factors (TFs) display different activation dynamics that trigger the expression of specific sets of target genes, suggesting that promoters have a way to decode dynamics. Here, we use optogenetics to directly manipulate the nuclear localization of...

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Detalles Bibliográficos
Autores principales: Antwi, Enoch B, Marrakchi, Yassine, Çiçek, Özgün, Brox, Thomas, Di Ventura, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201446/
https://www.ncbi.nlm.nih.gov/pubmed/37070176
http://dx.doi.org/10.1093/nar/gkad273