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Structures, activity and mechanism of the Type IIS restriction endonuclease PaqCI

Type IIS restriction endonucleases contain separate DNA recognition and catalytic domains and cleave their substrates at well-defined distances outside their target sequences. They are employed in biotechnology for a variety of purposes, including the creation of gene-targeting zinc finger and TAL e...

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Detalles Bibliográficos
Autores principales: Kennedy, Madison A, Hosford, Christopher J, Azumaya, Caleigh M, Luyten, Yvette A, Chen, Minyong, Morgan, Richard D, Stoddard, Barry L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201449/
https://www.ncbi.nlm.nih.gov/pubmed/36987874
http://dx.doi.org/10.1093/nar/gkad228