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Structures, activity and mechanism of the Type IIS restriction endonuclease PaqCI
Type IIS restriction endonucleases contain separate DNA recognition and catalytic domains and cleave their substrates at well-defined distances outside their target sequences. They are employed in biotechnology for a variety of purposes, including the creation of gene-targeting zinc finger and TAL e...
Autores principales: | Kennedy, Madison A, Hosford, Christopher J, Azumaya, Caleigh M, Luyten, Yvette A, Chen, Minyong, Morgan, Richard D, Stoddard, Barry L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201449/ https://www.ncbi.nlm.nih.gov/pubmed/36987874 http://dx.doi.org/10.1093/nar/gkad228 |
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