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PGC-1α overexpression is not sufficient to mitigate cancer cachexia in either male or female mice

Cancer cachexia (CC) accounts for 20%–40% of cancer-related deaths. Mitochondrial aberrations have been shown to precede muscle atrophy in different atrophy models, including cancer. Therefore, this study investigated potential protection from the cachectic phenotype through overexpression of peroxi...

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Detalles Bibliográficos
Autores principales:	Morena da Silva, Francielly, Rosa-Caldwell, Megan E., Schrems, Eleanor R., Martinez, Lauren, Amos, Madeline G., Lim, Seongkyun, Cabrera, Ana Regina, Brown, Jacob L., Washington, Tyrone A., Greene, Nicholas P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201462/ https://www.ncbi.nlm.nih.gov/pubmed/35700525 http://dx.doi.org/10.1139/apnm-2022-0086

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