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A state-of-the-art methodology for high-throughput in silico vaccine discovery against protozoan parasites and exemplified with discovered candidates for Toxoplasma gondii

Vaccine discovery against eukaryotic parasites is not trivial as highlighted by the limited number of known vaccines compared to the number of protozoal diseases that need one. Only three of 17 priority diseases have commercial vaccines. Live and attenuated vaccines have proved to be more effective...

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Detalles Bibliográficos
Autores principales: Goodswen, Stephen J., Kennedy, Paul J., Ellis, John T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201501/
https://www.ncbi.nlm.nih.gov/pubmed/37217589
http://dx.doi.org/10.1038/s41598-023-34863-9