Tautomerisation Mechanisms in the Adenine-Thymine Nucleobase Pair during DNA Strand Separation

[Image: see text] The adenine-thymine tautomer (A*-T*) has previously been discounted as a spontaneous mutagenesis mechanism due to the energetic instability of the tautomeric configuration. We study the stability of A*-T* while the nucleobases undergo DNA strand separation. Our calculations indicat...

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Detalles Bibliográficos
Autores principales: King, Benjamin, Winokan, Max, Stevenson, Paul, Al-Khalili, Jim, Slocombe, Louie, Sacchi, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201536/
https://www.ncbi.nlm.nih.gov/pubmed/36939840
http://dx.doi.org/10.1021/acs.jpcb.2c08631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201536/
https://www.ncbi.nlm.nih.gov/pubmed/36939840
http://dx.doi.org/10.1021/acs.jpcb.2c08631

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