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Mass spectrometry-based assays for assessing replicative bypass and repair of DNA alkylation in cells

Endogenous metabolism and environmental exposure can give rise to DNA alkylation, which can elicit deleterious biological consequences. In the search for reliable and quantitative analytical methods to elucidate the impact of DNA alkylation on the flow of genetic information, mass spectrometry (MS)...

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Detalles Bibliográficos
Autores principales: Li, Jiaxian, Hu, Zhihai, Liu, Dandan, Wang, Pengcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201546/
https://www.ncbi.nlm.nih.gov/pubmed/37223415
http://dx.doi.org/10.1039/d2ra08340j