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Metformin ameliorates HMGB1-mediated oxidative stress through mTOR pathway in experimental periodontitis
Periodontitis is an oral chronic inflammatory disease. Inhibiting tissue destruction and promoting tissue regeneration are important means for the treatment of periodontitis. Metformin not only has hypoglycemic effect but also has anti-inflammatory effect. Metformin has been shown to inhibit oxidati...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chongqing Medical University
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201554/ https://www.ncbi.nlm.nih.gov/pubmed/37223504 http://dx.doi.org/10.1016/j.gendis.2021.06.003 |