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Metformin ameliorates HMGB1-mediated oxidative stress through mTOR pathway in experimental periodontitis

Periodontitis is an oral chronic inflammatory disease. Inhibiting tissue destruction and promoting tissue regeneration are important means for the treatment of periodontitis. Metformin not only has hypoglycemic effect but also has anti-inflammatory effect. Metformin has been shown to inhibit oxidati...

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Detalles Bibliográficos
Autores principales: Sun, Boyang, Ying, Siqi, Ma, Qian, Li, Han, Li, Jie, Song, Jinlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201554/
https://www.ncbi.nlm.nih.gov/pubmed/37223504
http://dx.doi.org/10.1016/j.gendis.2021.06.003