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Mechanisms of NLRP3 inflammasome-mediated hepatic stellate cell activation: Therapeutic potential for liver fibrosis

The liver injury leads to an inflammatory response, which causes the activation of hepatic stellate cells (HSCs) that further secrete ECM proteins and play an important role in liver fibrosis. Moreover, the inflammatory response is a driving force for fibrogenesis, which is triggered by many types o...

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Detalles Bibliográficos
Autores principales: Charan, Harsh Vardhan, Dwivedi, Durgesh Kumar, Khan, Sabbir, Jena, Gopabandhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201559/
https://www.ncbi.nlm.nih.gov/pubmed/37223529
http://dx.doi.org/10.1016/j.gendis.2021.12.006