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Cathepsin K contributed to disturbed flow-induced atherosclerosis is dependent on integrin-actin cytoskeleton–NF–κB pathway

Atherosclerosis is a chronic inflammatory disease, occurring preferentially in bifurcation, branching, and bending of blood vessels exposed to disturbed flow. Disturbed flow in atheroprone areas activates elevated proteases, degrading elastin lamellae and collagenous matrix, resulting in endothelial...

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Detalles Bibliográficos
Autores principales: Fang, Fei, Feng, Tang, Li, Jianwei, Zhang, Huaiyi, Wang, Qin, Chen, Yidan, Wang, Guixue, Shen, Yang, Liu, Xiaoheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201601/
https://www.ncbi.nlm.nih.gov/pubmed/37223522
http://dx.doi.org/10.1016/j.gendis.2022.03.020