Cargando…
Cathepsin K contributed to disturbed flow-induced atherosclerosis is dependent on integrin-actin cytoskeleton–NF–κB pathway
Atherosclerosis is a chronic inflammatory disease, occurring preferentially in bifurcation, branching, and bending of blood vessels exposed to disturbed flow. Disturbed flow in atheroprone areas activates elevated proteases, degrading elastin lamellae and collagenous matrix, resulting in endothelial...
Autores principales: | Fang, Fei, Feng, Tang, Li, Jianwei, Zhang, Huaiyi, Wang, Qin, Chen, Yidan, Wang, Guixue, Shen, Yang, Liu, Xiaoheng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chongqing Medical University
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201601/ https://www.ncbi.nlm.nih.gov/pubmed/37223522 http://dx.doi.org/10.1016/j.gendis.2022.03.020 |
Ejemplares similares
-
Inflammatory endothelium-targeted and cathepsin responsive nanoparticles are effective against atherosclerosis
por: Fang, Fei, et al.
Publicado: (2022) -
CXCL chemokines-mediated communication between macrophages and BMSCs on titanium surface promotes osteogenesis via the actin cytoskeleton pathway
por: Zhang, Yayun, et al.
Publicado: (2023) -
Melatonin antagonizes ovarian aging via YTHDF2-MAPK-NF-κB pathway
por: Zhu, Ruigong, et al.
Publicado: (2020) -
Comparison of backbone dynamics of the p50 dimerization domain of NFκB in the homodimeric transcription factor NFκB1 and in its heterodimeric complex with RelA (p65)
por: Kohl, Bastian, et al.
Publicado: (2019) -
A heterozygous N-terminal truncation mutation of NFKBIA results in an impaired NF-κB dependent inflammatory response
por: Wen, Wen, et al.
Publicado: (2021)