Substrate binding in the allosteric site mimics homotropic cooperativity in the SIS‐fold glucosamine‐6‐phosphate deaminases

Glucosamine‐6‐phosphate (GlcN6P) deaminases from Escherichia coli (EcNagBI) and Shewanella denitrificans (SdNagBII) are special examples of what constitute nonhomologous isofunctional enzymes due to their convergence, not only in catalysis, but also in cooperativity and allosteric properties. Additi...

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Detalles Bibliográficos
Autores principales: Marcos‐Viquez, Jorge, Rodríguez‐Hernández, Annia, Álvarez‐Añorve, Laura I., Medina‐García, Andrea, Plumbridge, Jacqueline, Calcagno, Mario L., Rodríguez‐Romero, Adela, Bustos‐Jaimes, Ismael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Full‐length Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201695/
https://www.ncbi.nlm.nih.gov/pubmed/37145875
http://dx.doi.org/10.1002/pro.4651

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201695/
https://www.ncbi.nlm.nih.gov/pubmed/37145875
http://dx.doi.org/10.1002/pro.4651

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