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RNF182 induces p65 ubiquitination to affect PDL1 transcription and suppress immune evasion in lung adenocarcinoma

BACKGROUND: The RING finger (RNF) proteins are a large group of ubiquitin ligases whose aberrant expression is often associated with disease progression. This study examines the function of RNF protein 182 (RNF182) in lung adenocarcinoma (LUAD) cells and its impact on p65 and programmed death ligand...

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Detalles Bibliográficos
Autores principales: Zeng, Xingdu, Tang, Xiaoyuan, Chen, Xingxiang, Wen, Huilan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201958/
https://www.ncbi.nlm.nih.gov/pubmed/37249301
http://dx.doi.org/10.1002/iid3.864