Molecular basis of differential HLA class I-restricted T cell recognition of a highly networked HIV peptide

Cytotoxic-T-lymphocyte (CTL) mediated control of HIV-1 is enhanced by targeting highly networked epitopes in complex with human-leukocyte-antigen-class-I (HLA-I). However, the extent to which the presenting HLA allele contributes to this process is unknown. Here we examine the CTL response to QW9, a...

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Detalles Bibliográficos
Autores principales: Li, Xiaolong, Singh, Nishant Kumar, Collins, David R., Ng, Robert, Zhang, Angela, Lamothe-Molina, Pedro A., Shahinian, Peter, Xu, Shutong, Tan, Kemin, Piechocka-Trocha, Alicja, Urbach, Jonathan M., Weber, Jeffrey K., Gaiha, Gaurav D., Takou Mbah, Overbeck Christian, Huynh, Tien, Cheever, Sophia, Chen, James, Birnbaum, Michael, Zhou, Ruhong, Walker, Bruce D., Wang, Jia-huai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202051/
https://www.ncbi.nlm.nih.gov/pubmed/37217466
http://dx.doi.org/10.1038/s41467-023-38573-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202051/
https://www.ncbi.nlm.nih.gov/pubmed/37217466
http://dx.doi.org/10.1038/s41467-023-38573-8

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