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Indoleamine-2,3 dioxygenase: a fate-changer of the tumor microenvironment

Indoleamine-2,3 dioxygenase is a rate-limiting enzyme in the tryptophan catabolism in kynurenine pathways that has an immunosuppressive effect and supports cancer cells to evade the immune system in different cancer types. Diverse cytokines and pathways upregulate the production of indoleamine-2,3 d...

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Detalles Bibliográficos
Autores principales: Azimnasab-sorkhabi, Parviz, Soltani-asl, Maryam, Yoshinaga, Túlio Teruo, Zaidan Dagli, Maria Lucia, Massoco , Cristina de Oliveira, Kfoury Junior, Jose Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202066/
https://www.ncbi.nlm.nih.gov/pubmed/37217614
http://dx.doi.org/10.1007/s11033-023-08469-3