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A germline-targeted genetic screen for xrn-2 suppressors identifies a novel gene C34C12.2 in Caenorhabditis elegans

XRN2 is an evolutionarily conserved 5’-to-3’ exoribonuclease, which degrades or trims various types of RNA in the nucleus. Although XRN-2 is essential for embryogenesis, larval development and reproduction in Caenorhabditis elegans, relevant molecular pathways remain unidentified. Here we create a g...

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Detalles Bibliográficos
Autores principales: Aygün, Ilkin, Rzepczak, Alicja, Miki, Takashi S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202090/
https://www.ncbi.nlm.nih.gov/pubmed/37216322
http://dx.doi.org/10.1590/1678-4685-GMB-2022-0328