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The Influence of Cytochrome P450 Polymorphisms on Pharmacokinetic Profiles and Treatment Outcomes Among Malaria Patients in Sub-Saharan Africa: A Systematic Review

BACKGROUND: Sub-Saharan Africa (SSA) population is genetically diverse and heterogenous thus variability in drug response among individuals is predicted to be high. Cytochrome P450 (CYP450) polymorphisms is a major source of variability in drug response. This systematic review presents the influence...

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Detalles Bibliográficos
Autores principales: Marwa, Karol J, Kapesa, Anthony, Kamugisha, Erasmus, Swedberg, Göte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202199/
https://www.ncbi.nlm.nih.gov/pubmed/37223718
http://dx.doi.org/10.2147/PGPM.S379945