Round-window delivery of lithium chloride regenerates cochlear synapses damaged by noise-induced excitotoxic trauma via inhibition of the NMDA receptor in the rat

Noise exposure can destroy the synaptic connections between hair cells and auditory nerve fibers without damaging the hair cells, and this synaptic loss could contribute to difficult hearing in noisy environments. In this study, we investigated whether delivering lithium chloride to the round-window...

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Detalles Bibliográficos
Autores principales: Choi, Ji Eun, Carpena, Nathaniel T., Lee, Jae-Hun, Chang, So-Young, Lee, Min Young, Jung, Jae Yun, Chung, Won-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202264/
https://www.ncbi.nlm.nih.gov/pubmed/37216352
http://dx.doi.org/10.1371/journal.pone.0284626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202264/
https://www.ncbi.nlm.nih.gov/pubmed/37216352
http://dx.doi.org/10.1371/journal.pone.0284626

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