GAD65 deficient mice are susceptible to ethanol-induced impairment of motor coordination and facilitation of cerebellar neuronal firing

γ-aminobutyric acid (GABA) is a major inhibitory neurotransmitter and its concentrations in the brain could be associated with EtOH-induced impairment of motor coordination. GABA is synthesized by two isoforms of glutamate decarboxylase (GAD): GAD65 and GAD67. Mice deficient in GAD65 (GAD65-KO) can...

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Detalles Bibliográficos
Autores principales: Matsunaga, Wataru, Shinoe, Toru, Hirono, Moritoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202268/
https://www.ncbi.nlm.nih.gov/pubmed/37216370
http://dx.doi.org/10.1371/journal.pone.0286031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202268/
https://www.ncbi.nlm.nih.gov/pubmed/37216370
http://dx.doi.org/10.1371/journal.pone.0286031

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