Bcl-xL is required to protect endothelial cells latently infected with KSHV from virus induced intrinsic apoptosis

Kaposi’s Sarcoma herpesvirus (KSHV) is the etiologic agent of Kaposi’s Sarcoma (KS), a highly vascularized tumor common in AIDS patients and many countries in Africa. KSHV is predominantly in the latent state in the main KS tumor cell, the spindle cell, a cell expressing endothelial cell markers. To...

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Detalles Bibliográficos
Autores principales: Moore, Lyndsey N., Holmes, Daniel L., Sharma, Anjali, Landazuri Vinueza, Joselyn, Lagunoff, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202281/
https://www.ncbi.nlm.nih.gov/pubmed/37163552
http://dx.doi.org/10.1371/journal.ppat.1011385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202281/
https://www.ncbi.nlm.nih.gov/pubmed/37163552
http://dx.doi.org/10.1371/journal.ppat.1011385

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