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Striatal CDK5 Regulates Cholinergic Neuron Activation and Dyskinesia-like Behaviors through BK Channels

Disturbance of the cholinergic system plays a crucial role in the pathological progression of neurological diseases that cause dyskinesia-like behaviors. However, the molecular mechanisms underlying this disturbance remain elusive. Here, we showed that cyclin-dependent kinase 5 (Cdk5) was reduced in...

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Detalles Bibliográficos
Autores principales: Tong, Chu, Min, Peng-Xiang, Zhang, Qian, Gu, Ru-Xin, Wen, Yao-Hai, Shi, Yi, Bao, Yu-Huan, Chen, Xiang, Zhang, Yi-Xuan, Mao, Xing-Feng, Yuan, Hao-Yang, Liu, Xiu-Xiu, Sasaki, Takuya, Zhang, Li, Han, Feng, Lu, Ying-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAAS 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202382/
https://www.ncbi.nlm.nih.gov/pubmed/37223477
http://dx.doi.org/10.34133/research.0121