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The First-in-Human Whole-Body Dynamic Pharmacokinetics Study of Aptamer

Serving as targeting ligands, aptamers have shown promise in precision medicine. However, the lack of knowledge of the biosafety and metabolism patterns in the human body largely impeded aptamers’ clinical translation. To bridge this gap, here we report the first-in-human pharmacokinetics study of p...

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Detalles Bibliográficos
Autores principales: Ding, Ding, Zhao, Haitao, Wei, Dali, Yang, Qinglai, Yang, Cai, Wang, Ruowen, Chen, Yumei, Li, Lianghua, An, Shuxian, Xia, Qian, Huang, Gang, Liu, Jianjun, Xiao, Zeyu, Tan, Weihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAAS 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202413/
https://www.ncbi.nlm.nih.gov/pubmed/37223462
http://dx.doi.org/10.34133/research.0126