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pYtags enable spatiotemporal measurements of receptor tyrosine kinase signaling in living cells

Receptor tyrosine kinases (RTKs) are major signaling hubs in metazoans, playing crucial roles in cell proliferation, migration, and differentiation. However, few tools are available to measure the activity of a specific RTK in individual living cells. Here, we present pYtags, a modular approach for...

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Detalles Bibliográficos
Autores principales: Farahani, Payam E, Yang, Xiaoyu, Mesev, Emily V, Fomby, Kaylan A, Brumbaugh-Reed, Ellen H, Bashor, Caleb J, Nelson, Celeste M, Toettcher, Jared E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202457/
https://www.ncbi.nlm.nih.gov/pubmed/37212240
http://dx.doi.org/10.7554/eLife.82863