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The RNA-binding protein QKI governs a muscle-specific alternative splicing program that shapes the contractile function of cardiomyocytes

AIMS: In the heart, splicing factors orchestrate the functional properties of cardiomyocytes by regulating the alternative splicing of multiple genes. Work in embryonic stem cells has shown that the splicing factor Quaking (QKI) regulates alternative splicing during cardiomyocyte differentiation. Ho...

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Detalles Bibliográficos
Autores principales: Montañés-Agudo, Pablo, Aufiero, Simona, Schepers, Eva N, van der Made, Ingeborg, Cócera-Ortega, Lucia, Ernault, Auriane C, Richard, Stéphane, Kuster, Diederik W D, Christoffels, Vincent M, Pinto, Yigal M, Creemers, Esther E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202634/
https://www.ncbi.nlm.nih.gov/pubmed/36627242
http://dx.doi.org/10.1093/cvr/cvad007