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Generation, genomic characterization, and differentiation of triploid human embryonic stem cells

Humans are diploid organisms, and triploidy in human embryos is responsible for ∼10% of spontaneous miscarriages. Surprisingly, some pregnancies proceed to triploid newborns that suffer from many neuro-developmental disorders. To investigate the impact of triploidy on human development, we generate...

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Detalles Bibliográficos
Autores principales: Haim-Abadi, Guy, Golan-Lev, Tamar, Koren, Amnon, Benvenisty, Nissim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202691/
https://www.ncbi.nlm.nih.gov/pubmed/37116485
http://dx.doi.org/10.1016/j.stemcr.2023.04.001