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Generation, genomic characterization, and differentiation of triploid human embryonic stem cells
Humans are diploid organisms, and triploidy in human embryos is responsible for ∼10% of spontaneous miscarriages. Surprisingly, some pregnancies proceed to triploid newborns that suffer from many neuro-developmental disorders. To investigate the impact of triploidy on human development, we generate...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202691/ https://www.ncbi.nlm.nih.gov/pubmed/37116485 http://dx.doi.org/10.1016/j.stemcr.2023.04.001 |