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Single-cell transcriptome analysis of xenotransplanted human retinal organoids defines two migratory cell populations of nonretinal origin

Human retinal organoid transplantation could potentially be a treatment for degenerative retinal diseases. How the recipient retina regulates the survival, maturation, and proliferation of transplanted organoid cells is unknown. We transplanted human retinal organoid-derived cells into photoreceptor...

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Detalles Bibliográficos
Autores principales: Liu, Ying V., Santiago, Clayton P., Sogunro, Akin, Konar, Gregory J., Hu, Ming-wen, McNally, Minda M., Lu, Yu-chen, Flores-Bellver, Miguel, Aparicio-Domingo, Silvia, Li, Kang V., Li, Zhuo-lin, Agakishiev, Dzhalal, Hadyniak, Sarah E., Hussey, Katarzyna A., Creamer, Tyler J., Orzolek, Linda D., Teng, Derek, Canto-Soler, M. Valeria, Qian, Jiang, Jiang, Zheng, Johnston, Robert J., Blackshaw, Seth, Singh, Mandeep S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202694/
https://www.ncbi.nlm.nih.gov/pubmed/37163980
http://dx.doi.org/10.1016/j.stemcr.2023.04.004