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Effects of intravenous infusion, vest wearing and repeated intravenous blood collection on clinical pathology parameters in cynomolgus monkeys (Macaca fascicularis)

Nonhuman primates are used extensively in a variety of nonclinical safety evaluation studies of new drugs. In those studies, intravenous infusion is a common treatment method, a noninvasive telemetry system is usually used for cardiovascular safety and pharmacology evaluation, and blood samples are...

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Detalles Bibliográficos
Autores principales: Zhao, Qi, Li, Caiyun, Chen, Yan, Liu, Yongtao, Wang, Shuyan, Wang, Xijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202713/
https://www.ncbi.nlm.nih.gov/pubmed/36543206
http://dx.doi.org/10.1538/expanim.22-0106