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Deficiency of IRG1/ itaconate aggravates endotoxemia-induced acute lung injury by inhibiting autophagy in mice

Itaconate, produced by aconitate decarboxylase 1 (ACOD1), which is encoded by immune-responsive gene 1 (Irg1), is one of the metabolites derived from the tricarboxylic acid cycle. It has been reported that exogenous itaconate plays an anti-inflammatory role in the progression of multiple diseases an...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Qiu, Jing-Huan, Zhang, Li, Li, Ke-Xin, Zhang, Qiu-Hong, Fan, Ke-Rui, Chen, Kun, Jiang, Yu, Liu, Gang
বিন্যাস: Online প্রবন্ধ পাঠ‍্য
ভাষা:English
প্রকাশিত: Japanese Association for Laboratory Animal Science 2022
বিষয়গুলি:
অনলাইন ব্যবহার করুন:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202714/
https://www.ncbi.nlm.nih.gov/pubmed/36288955
http://dx.doi.org/10.1538/expanim.22-0104