Phase separation of DDX21 promotes colorectal cancer metastasis via MCM5-dependent EMT pathway

RNA binding proteins (RBPs) contributes to cancer progression, but the underlying mechanism reminds unclear. Here, we find that DDX21, a representative RBP, is highly expressed in colorectal cancer (CRC), which leads to CRC cell migration and invasion in vitro, and CRC to liver metastasis and lung m...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, Huabin, Wei, Huiting, Yang, Yang, Li, Hui, Liang, Jiangtao, Ye, Jiecheng, Zhang, Fenfen, Wang, Liyuan, Shi, Huijuan, Wang, Jia, Han, Anjia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202810/
https://www.ncbi.nlm.nih.gov/pubmed/37029300
http://dx.doi.org/10.1038/s41388-023-02687-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202810/
https://www.ncbi.nlm.nih.gov/pubmed/37029300
http://dx.doi.org/10.1038/s41388-023-02687-6

Ejemplares similares