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Phase separation of DDX21 promotes colorectal cancer metastasis via MCM5-dependent EMT pathway

RNA binding proteins (RBPs) contributes to cancer progression, but the underlying mechanism reminds unclear. Here, we find that DDX21, a representative RBP, is highly expressed in colorectal cancer (CRC), which leads to CRC cell migration and invasion in vitro, and CRC to liver metastasis and lung m...

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Detalles Bibliográficos
Autores principales:	Gao, Huabin, Wei, Huiting, Yang, Yang, Li, Hui, Liang, Jiangtao, Ye, Jiecheng, Zhang, Fenfen, Wang, Liyuan, Shi, Huijuan, Wang, Jia, Han, Anjia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202810/ https://www.ncbi.nlm.nih.gov/pubmed/37029300 http://dx.doi.org/10.1038/s41388-023-02687-6

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