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Autoinhibitory mechanism controls binding of centrosomin motif 1 to γ-tubulin ring complex

The γ-tubulin ring complex (γTuRC) is the principal nucleator of cellular microtubules, and the microtubule-nucleating activity of the complex is stimulated by binding to the γTuRC-mediated nucleation activator (γTuNA) motif. The γTuNA is part of the centrosomin motif 1 (CM1), which is widely found...

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Detalles Bibliográficos
Autores principales: Yang, Shaozhong, Au, Franco K.C., Li, Gefei, Lin, Jianwei, Li, Xiang David, Qi, Robert Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202828/
https://www.ncbi.nlm.nih.gov/pubmed/37213089
http://dx.doi.org/10.1083/jcb.202007101