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Inhibition of endolysosome fusion increases exosome secretion

Exosomes are small vesicles that are secreted from cells to dispose of undegraded materials and mediate intercellular communication. A major source of exosomes is intraluminal vesicles within multivesicular endosomes that undergo exocytic fusion with the plasma membrane. An alternative fate of multi...

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Detalles Bibliográficos
Autores principales: Shelke, Ganesh Vilas, Williamson, Chad D., Jarnik, Michal, Bonifacino, Juan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202829/
https://www.ncbi.nlm.nih.gov/pubmed/37213076
http://dx.doi.org/10.1083/jcb.202209084