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Small lipid droplets are rigid enough to indent a nucleus, dilute the lamina, and cause rupture
The nucleus in many cell types is a stiff organelle, but fat-filled lipid droplets (FDs) in cytoplasm are seen to indent and displace the nucleus. FDs are phase-separated liquids with a poorly understood interfacial tension γ that determines how FDs interact with other organelles. Here, micron-sized...
Autores principales: | Ivanovska, Irena L., Tobin, Michael P., Bai, Tianyi, Dooling, Lawrence J., Discher, Dennis E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202833/ https://www.ncbi.nlm.nih.gov/pubmed/37212777 http://dx.doi.org/10.1083/jcb.202208123 |
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