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MANF ameliorates DSS-induced mouse colitis via restricting Ly6C(hi)CX3CR1(int) macrophage transformation and suppressing CHOP-BATF2 signaling pathway

Mesencephalic astrocyte-derived neurotrophic factor (MANF), an endoplasmic reticulum stress-inducible secreting protein, has evolutionarily conserved immune-regulatory function that contributes to the negative regulation of inflammation in macrophages. In this study, we investigated the profiles of...

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Detalles Bibliográficos
Autores principales: Yang, Lin, Shen, Wen-wen, Shao, Wei, Zhao, Qing, Pang, Gao-zong, Yang, Yi, Tao, Xiao-fang, Zhang, Wei-ping, Mei, Qiong, Shen, Yu-xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202914/
https://www.ncbi.nlm.nih.gov/pubmed/36635421
http://dx.doi.org/10.1038/s41401-022-01045-8