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Linear time complexity de novo long read genome assembly with GoldRush

Current state-of-the-art de novo long read genome assemblers follow the Overlap-Layout-Consensus paradigm. While read-to-read overlap – its most costly step – was improved in modern long read genome assemblers, these tools still often require excessive RAM when assembling a typical human dataset. Ou...

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Detalles Bibliográficos
Autores principales: Wong, Johnathan, Coombe, Lauren, Nikolić, Vladimir, Zhang, Emily, Nip, Ka Ming, Sidhu, Puneet, Warren, René L., Birol, Inanç
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202940/
https://www.ncbi.nlm.nih.gov/pubmed/37217507
http://dx.doi.org/10.1038/s41467-023-38716-x