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Linear time complexity de novo long read genome assembly with GoldRush
Current state-of-the-art de novo long read genome assemblers follow the Overlap-Layout-Consensus paradigm. While read-to-read overlap – its most costly step – was improved in modern long read genome assemblers, these tools still often require excessive RAM when assembling a typical human dataset. Ou...
Autores principales: | Wong, Johnathan, Coombe, Lauren, Nikolić, Vladimir, Zhang, Emily, Nip, Ka Ming, Sidhu, Puneet, Warren, René L., Birol, Inanç |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202940/ https://www.ncbi.nlm.nih.gov/pubmed/37217507 http://dx.doi.org/10.1038/s41467-023-38716-x |
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