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Circlehunter: a tool to identify extrachromosomal circular DNA from ATAC-Seq data

In cancer, extrachromosomal circular DNA (ecDNA), or megabase-pair amplified circular DNA, plays an essential role in intercellular heterogeneity and tumor cell revolution because of its non-Mendelian inheritance. We developed circlehunter (https://github.com/suda-huanglab/circlehunter), a tool for...

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Detalles Bibliográficos
Autores principales: Yang, Manqiu, Zhang, Shufan, Jiang, Rong, Chen, Shaomu, Huang, Moli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202962/
https://www.ncbi.nlm.nih.gov/pubmed/37217468
http://dx.doi.org/10.1038/s41389-023-00476-0