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CRISPR-based functional genomics screening in human-pluripotent-stem-cell-derived cell types

While our knowledge of gene expression in different human cell types is rapidly expanding with advances in transcriptomic profiling technologies, the next challenge is to understand gene function in each cell type. CRISPR-Cas9-based functional genomics screening offers a powerful approach to determi...

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Detalles Bibliográficos
Autores principales: Li, Kun, Ouyang, Miao, Zhan, Jiangshan, Tian, Ruilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203043/
https://www.ncbi.nlm.nih.gov/pubmed/37228745
http://dx.doi.org/10.1016/j.xgen.2023.100300