Genome graphs detect human polymorphisms in active epigenomic state during influenza infection

Genetic variants, including mobile element insertions (MEIs), are known to impact the epigenome. We hypothesized that genome graphs, which encapsulate genetic diversity, could reveal missing epigenomic signals. To test this, we sequenced the epigenome of monocyte-derived macrophages from 35 ancestra...

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Detalles Bibliográficos
Autores principales: Groza, Cristian, Chen, Xun, Pacis, Alain, Simon, Marie-Michelle, Pramatarova, Albena, Aracena, Katherine A., Pastinen, Tomi, Barreiro, Luis B., Bourque, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203048/
https://www.ncbi.nlm.nih.gov/pubmed/37228750
http://dx.doi.org/10.1016/j.xgen.2023.100294

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203048/
https://www.ncbi.nlm.nih.gov/pubmed/37228750
http://dx.doi.org/10.1016/j.xgen.2023.100294

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